Crop Biotechnology: Feeds for the Dairy Industry

Bruce R. Thomas, Kent J. Bradford
Seed Biotechnology Center, Univ. California, Davis
(http://sbc.ucdavis.edu)(email: sbc@ucdavis.edu)

Lecture at Dairy Cattle Day, UC Davis, March 21, 2001

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Current Biotech Feed Crops
 Methods of plant breeding and biotechnology.  Genetic modification of plants and animals has been practiced for approximately 10,000 years.  By selecting the best plants and animals to serve as the parents for the next generation, our ancestors gradually modified wild plants and animals to create our familiar domesticated crops and livestock.  Over the last century, new methods of plant breeding have been introduced, including wide crosses, F1 hybridization, mutagenesis, and induction of polyploidy.  Biotechnology methods developed in the last few decades include tissue culture, embryo culture, anther culture, somaclonal variation, micropropagation, protoplast fusion, marker-assisted breeding, and transgenic plants.  The discussion below will focus on the transgenic crop plants used for livestock feeds.
Plant Biotechnology Tutorials - Resource Series
http://sbc.ucdavis.edu/outreach/resource/tutorial_biotech.htm
Plant Biotechnology Dictionaries - Resource Series
http://sbc.ucdavis.edu/outreach/resource/dictionary_biotech.htm

corn harvest
 Transgenic Crop Traits.  Among the transgenic crop plants approved by APHIS for commercial production in the US are canola, corn, cotton and soybeans engineered for herbicide compatibility and protection against insects.  Herbicide tolerance in transgenic crops provides better weed control and improves soil conservation.  Bt genes help to control insects in transgenic crops.  Mycotoxin contents are reduced in transgenic plants due to reduced insect feeding and fewer damaged sites at which fungal infection of the crop plant can occur.  Engineering pest protection traits into the seed may reduce the need for pesticide chemicals in crop production, and may enable the grower to choose pesticides that are less harmful to the environment.  Recent economic studies document benefits of transgenic crops including yield increases, cost savings to growers and reductions in chemical application.  These benefits have led to rapid adoption of transgenic crops on over 100 million acres worldwide.
USDA APHIS - New List of De-Regulated Crops
http://www.aphis.usda.gov/biotech/not_reg.html
Agricultural Biotechnology Briefing Room, ERS/USDA
http://www.ers.usda.gov/Briefing/Biotechnology/
Impacts of adopting genetically engineered crops in the United States, ERS USDA 07mar2001
http://www.ers.usda.gov/Emphases/Harmony/issues/genengcrops/genengcrops.htm
Agronomic & Economic Assessment of Transgenic Canola, Canola Council of Canada jan2001
http://www.canola-council.org/manual/GMO/gmo_main.htm
ISAAA Brief No. 21 - 2000 : Global Status of Commercialized Transgenic Crops
http://www.canola-council.org/manual/GMO/gmo_main.htm

 US Government Regulation of Transgenic Crops.  The use of crops produced via biotechnology is regulated by a number of US government agencies.  The USDA Animal and Plant Health Inspection Service (APHIS) regulates field-testing of biotechnology-derived plant varieties. The US Environmental Protection Agency (EPA) is the lead agency for evaluating crop plants with pesticidal traits developed via biotechnology. The US Food and Drug Administration (FDA) is the primary agency regulating the safety of foods developed via biotechnology. USDA has recently published new regulations for organic agriculture certification that exclude the use of transgenic crop plants and some other production technologies that are used in conventional agriculture. An additional consumer choice is provided by recent FDA regulations for voluntary labeling of foods produced without transgenic ingredients.
USDA - Agricultural Biotechnology
http://www.aphis.usda.gov/bbep/bp/
EPA - Biopesticides
http://www.epa.gov/pesticides/biopesticides/
FDA - Center for Food Safety and Applied Nutrition
http://vm.cfsan.fda.gov/
National Organic Standards - Final Rule
http://www.ams.usda.gov/nop/nop2000/nop/finalrulepages/finalrulemap.htm
FDA - voluntary labeling of foods produced without transgenic ingredients
http://www.cfsan.fda.gov/~dms/biolabgu.html

 International Government Regulation of Transgenic Crops.  Export markets for transgenic crops are very complicated at present. Public reactions to transgenics in other countries vary widely.  Many governments are still setting up mechanisms to regulate biotechnology crops and food products.  Two recent developments demonstrate some progress.  The European Union Parliament recently repealed the moratorium on approval of new genetically modified (GM) food crops.  Japan has set reasonable tolerance limits for small amounts of unintentional transgenic content in shipments of conventional crop products.
Repeal of moratorium on GMO release into the environment, European Parliament 29jan2001
http://www2.europarl.eu.int/omk/OM-Europarl?PROG=REPORT&L=EN&PUBREF=-//EP//TEXT
                      +REPORT+A5-2001-0032+0+NOT+SGML+V0//EN
The future of the biotechnology industry, Reports of the European Parliament 28feb2001
http://www2.europarl.eu.int/omk/OM-Europarl?PROG=REPORT&L=EN&PUBREF=-//EP//TEXT
                      +REPORT+A5-2001-0080+0+NOT+SGML+V0//EN
European Union parliament pledges support for GM technologies, Reuters 15march2001
http://www.plant.uoguelph.ca/safefood/archives/agnet/2001/3-2001/ag-03-15-01-02.txt
Japan to allow foods to contain up to 5 percent biotech, Tokyo (AP)  20march2001
http://agbioview.listbot.com/cgi-bin/subscriber?Act=view_message&list_id=agbioview&msg_num=1017&start_num=

Consumer survey.  A recent public survey in the US demonstrated that a majority expect biotechnology to provide benefits.  When asked about food safety issues, very few people indicated any concerns about biotechnology in foods.  Thus, in the US we are generally optimistic about biotechnology and believe that government regulation of the technology is working to protect public safety.
Wirthlin Group Quorum Survey of consumers in USA, Jan 2001
http://ific.org/   (What's New at IFIC)













 Feeding trials.  Feeding trials have demonstrated the safety and effectiveness of feeds derived from transgenic crop plants.  Transgenic feeds are digested normally, so there is no effect on safety of meat, milk or eggs produced by the livestock.
GM Food Safety Assessment - Resource Series
http://sbc.ucdavis.edu/outreach/resource/gm_food_safety.htm
Crop Biotechnology: Feeds for Livestock
http://sbc.ucdavis.edu/outreach/lecture/livestock_feeds.htm

Future Biotech Feed Crops
Potential future traits in transgenic crops include more "output traits" that will enhance food and feed qualities.  Transgenic crop traits that may reach the marketplace within the next 5 years include traits such as improved nutritional value through increased digestibility, oil quality and protein quality.  The content of antinutritional substances such as phytate can be reduced.  Vaccines delivered via feeds may help to maintain the health of livestock.  Use of antifungal peptides may reduce fungi and mycotoxins in feeds, thus improving feed quality, animal health and dairy product quality.  New strategies may help protect alfalfa and other plants against insect attack and reduce the need to spray chemicals for insect control.
USDA APHIS - Current Status of Notifications
http://www.aphis.usda.gov/bbep/bp/notday.html
USDA APHIS - Current Status of Petitions
http://www.aphis.usda.gov/biotech/petday.html
 
 

Conclusions
This is an important time in the development of agricultural biotechnology. The initial “proof of concept” transgenic crops have performed well in the field, providing agronomic and economic benefits to growers.  The first generation of transgenic crops have provided a safe and effective supply of feeds to livestock producers. New biotechnology crop traits under development will provide additional benefits to the dairy industry in the future.  Transgenic crops require fewer agrichemical applications which provides environmental benefits.

US government regulators have worked to establish public confidence in their ability to ensure the environmental and food safety of crop plants developed using biotechnology.  Export markets for transgenic crops are complicated by wide variability in international government regulations and consumer reactions to biotechnology.


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Dr. Kent J. Bradford
Director
Dr. Bruce R. Thomas
Technical Director
Susan Webster
Program Representative

Seed Biotechnology Center
University of California, One Shields Avenue, Davis CA 95616
Tel: 530-754-7333 . . . Fax: 530-754-7222
http://sbc.ucdavis.edu . . . email: sbc@ucdavis.edu